Lipid-lowering therapy of cardiovascular diseases (literature review)

Statins: Newer Roles Including Lipid Lowering Therapy

Statins are most effective pharmacologically agents to decrease total plasma cholesterol level by competitive inhibition of HMG-Co A reductase. Apart from the well-known LDL and cholesterol lowering effect, statins have been postulated to exert other beneficial effects also called pleotropic or non-lipid effects. Better understanding of various pleotropic effects of statins has prompted a new s...

Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins.

Cholesterol lowering involving different therapies improves the clinical outcome of patients. To define the underlying pathomechanism, we studied whether treatment with statins was associated with changes in blood thrombogenicity, endothelial dysfunction and soluble adhesion molecule levels. Fifty hypercholesterolemic patients were treated with pravastatin (40 mg/day, n=24) or simvastatin (20 m...

Is Photodynamic Therapy Effective in Treatment of Periodontal Diseases? A Review of Literature

Heterogeneity of response to lipid-lowering therapy.

the follow-up (from 3 to 2 and 0), simply after evaluating them, performing the tilt table test and explaining the pathogenesis of the disease. This fact may explain Dr. Sra’s (2) skepticism on the medical capacity to prove the benefit of any treatment for vasovagal syncope. This could also be the reason why almost any treatment that has been tested for the therapy of vasovagal syncope has been...

Reversal of Cardiovascular Toxicity in Severe Organophosphate Poisoning with 20% Intralipid Emulsion Therapy: Case Report and Review of Literature

Background: Cardiac toxicity is one of the life-threatening effects of severe organophosphate (OP) poisoning. We presented a patient with severe OP poisoning, in cardiovascular shock poorly responsive to conventional treatments, who could be resuscitated successfully with intravenous lipid emulsion (ILE) therapy. Case report: A 26-year-old female was admitted to our emergency department who had...